Aromatic Benzoyloxylation with Benzoyl Peroxide-Iodine

Tretinoin and Benzoyl Peroxide

A simple, sensitive, spectrophotometric method in UV region has been developed for the simultaneous estimation of benzoyl peroxide and tretinoin in bulk and semi solid dosage form (cream). Standard solution of benzoyl peroxide shows maximum absorbance at 234.8 nm and tretinoin shows maximum absorbance at 348.6 nm. Beer’s Lamberts law is obeyed in concentration range 1-9 μg/ml for tretinoin with...

Comparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study.

INTRODUCTION A solubilized 5% BPO gel has been developed to enhance the bioavailability, follicular penetration, and efficacy of BPO. METHODS Sixty-five patients with moderate facial acne vulgaris were randomly assigned to apply solubilized 5% BPO gel to one facial side and 5% BPO/1% clindamycin to the contralateral side, twice daily for four or 12 weeks. RESULTS The solubilized BPO gel res...

Efficacy of benzoyl peroxide (5.3%) emollient foam and benzoyl peroxide (8%) wash in reducing Propionibacterium acnes on the back.

BACKGROUND Topical treatment of acne vulgaris on the back is challenging largely due to the extensive broad surface with difficult to reach areas. A "leave-on" foam is suited for application to the trunk due to ease of application and spreadability. Prior to this trial, no data on Propionibacterium acnes (P. acnes) reduction on the back has existed for any benzoyl peroxide (BP) formulations or ...

Formulation and Characterization of Benzoyl Peroxide Gellified Emulsions

The present investigation was carried out with the objective of formulating a gellified emulsion of benzoyl peroxide, an anti-acne agent. The formulations were prepared using four different vegetable oils, viz. almond oil, jojoba oil, sesame oil, and wheat germ oil, owing to their emollient properties. The idea was to overcome the skin irritation and dryness caused by benzoyl peroxide, making t...

Ethyl lactate and benzoyl peroxide in acne vulgaris